Science University Research Symposium (SURS)

Publication Date

Winter 11-10-2025

College

College of Sciences & Mathematics

Department

Psychological Science, Department of

SURS Faculty Advisor

Dr. Jinhee Park

Presentation Type

Poster Presentation

Abstract

Zebrafish are a good organism model due to their similarities with human biology. The transparency of their embryos allows for an easier view to see the developmental stages of the embryos, and easily and accurately note any mutations or defects in any of the embryos. In addition, they make excellent candidates to track potential effects that mirror human embryos with ethanol and alcohol will have on their developmental stages. The aim of this study was to measure the genetic size developmental differences of the embryo’s lens, eyes, and heart that are given 1% alcohol and 2% alcohol. This study’s experimental design consisted of breeding the zebrafish on one day, once they laid eggs then we would create 3 different groups of alcohol and eggs. There was a control group that consisted of only eggs and 10 mL of egg water, a 1% group that contained 1% of alcohol and 10mL of egg water in a petri dish with the eggs, and a 2% group of eggs that were in same environment with 2% of alcohol and 10mL of egg water. After each condition was created, imaging would take place next to view how they embryos have developed.

Results showed that alcohol exposure caused developmental defects as the eggs developed into embryos. Specifically, the size of the eyes and lens became smaller, while the size of the heart increased significantly compared to the control group. The importance of this study is to showcase the potential mechanisms by which alcohol can negatively affect genetic development of humans.

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