DNP Scholarly Projects
Predictors of barriers to participation in clinical research in adults living in the Southeastern United States
Research is the necessary foundation for health care advancement and understanding. Significant challenges exist, however, with recruiting and engaging underrepresented populations in clinical research. The purpose of the scholarly project was to determine how stakeholder race, trust, and level of education influence participation barriers in clinical research. The project utilized secondary, cross sectional survey data that were collected between 2014 and 2016 through the former Mid-South Clinical Data Research Network (CDRN), currently known as the STAR-CRN. Descriptive statistics and spearman rank correlations were performed between level of education, level of trust, and each attitude statement for each racial category. A total of 2,149 survey responses were used in the data analysis. The mean age of respondents was 52 years old (SD=15.65) with majority being female (69.0%, n=1496), white (77.7%, n=1701), insured (76%, n=1610), and working full time (50.4%, n=1078). Overall, the respondents had favorable attitudes towards research participation. Trust was associated with agreement in each attitude statement from both white and AA respondents (pCC=-.492; p=.000), AA (CC=-.188; p=.000), Asian (CC=-.429; p=.041), and Middle Eastern (CC=-.864; p=.003) respondents. The results support the importance of trust within the patient and provider relationship. Generally, education level is not a largely predictive variable in its influence of research participation, although it shows stronger evidence of influence depending on race and attitude statement.
Keywords: trust, race, education, participation, clinical research, underrepresented, adults
Dr. Linda Wofford, DNP
Dr. David Philippi, PhD
Scholarly Project Team Member
Alecia Fair, DrPH
Nursing, School of
Health Sciences & Nursing, Gordon E. Inman College of
Doctorate of Nursing Practice (DNP)
trust; race; education; participation; clinical research; underrepresented adults; willingness to participate
Scanlon, Jennifer, "Predictors of barriers to participation in clinical research in adults living in the Southeastern United States" (2020). DNP Scholarly Projects. 38.