Belmont University Research Symposium (BURS)

Using Microfluidics to Sort Cells by Size

Publication Date

2024

College

Sciences and Mathematics, College of

Department

Chemistry and Physics, Department of

BURS Faculty Advisor

Dr. Krista McBride

Presentation Type

Oral Presentation

Abstract

All throughout healthcare, analyzing a sample of cells can be a gateway into the truth of a patient and can often lead to life saving treatment. Whether it is to diagnose someone with a chronic disease, cancer, or just for a checkup, our cells provide insight into our wellbeing. Sorting cells can often be a difficult and time consuming task, however, and in dire situations that could lead to the loss of a patient. Microfluidics is actively changing the way we go about conducting analysis throughout scientific fields. Microfluidics is the study of fluid dynamics on the micro scale. At this scale, fluid dynamics takes on different attributes that allow for
unprecedented levels of control over systems. This article outlines a form of microfluidics
known as chip microfluidics which uses the foil embossing method to imprint micro channels in
PDMS. In this article, the micro channels are in a spiral shape in order to effectively use Dean
Flow, a type of flow in curved channels, to sort cells by size.

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